Gender differences in masticatory movement path and rhythm in dentate adults

PurposeThe purpose of this study was to clarify whether there might be a gender difference in masticatory movement path and rhythm in dentate adults.MethodsThirty healthy males and 30 healthy females were asked to chew softened chewing gum on their habitual chewing side for 20 sec, and the movement of the mandibular incisal point was recorded using mandibular kinesiograph. For 10 cycles from the fifth cycle, the spatial and temporal parameters (spatial: amounts of vertical and lateral movements; temporal: opening, closing, occluding, and cycle times) of masticatory movement path and rhythm and the parameters representing the stability of masticatory movement path and rhythm were calculated and compared between males and females.ResultsThe values of the spatial parameters were significantly greater for males than for females. The values of the temporal parameters were smaller for males than for females, and significant differences were found in all parameters except occluding time. However, there was no statistically significant difference in the parameters representing the stability of masticatory movement path and rhythm.ConclusionFrom these results it was suggested that although there were no differences in the stability of masticatory movement path and rhythm between genders, there were gender differences in the spatial and temporal parameters of masticatory movement path and rhythm.     

实施辅助生殖技术女性患者自我接纳与主观幸福感的关系研究

目的探讨实施辅助生殖技术女性患者自我接纳与主观幸福感的关系。方法采用自我接纳问卷和纽芬兰大学幸福度量表,对268例实施辅助生殖技术的女性患者进行问卷调查。结果实施辅助生殖技术的女性患者的自我接纳及主观幸福感均处于中等偏低水平,自我接纳总分及其各维度与主观幸福感总分、正性情感及正性体验呈显著正相关,与负性情感及负性体验呈显著负相关。自我接纳及自我评价是实施辅助生殖技术的女性患者主观幸福感的正向预测因子。结论自我接纳是实施辅助生殖技术的女性患者主观幸福感的重要影响因素。     

脂多糖通过Toll样受体对雄性生殖功能的影响

生殖道感染是影响男性生育的重要因素之一,然而其机制尚未完全明了。最近研究认为病原体模式识别受体之一Toll样受体(TLRs)及其诱导的信号通路在炎症导致雄性不育过程中发挥着重要作用。脂多糖(LPS)作为革兰阴性菌细胞壁组成成分,可以通过TLRs诱导相应的炎症反应。众多研究表明,TLRs在雄性生殖道广泛表达,并且LPS可通过TLRs诱导生殖道炎症反应,影响雄性生殖功能。本文就LPS通过其相关受体TLRs通路诱导生殖道炎症,影响睾丸、附睾功能及精子质量,导致雄性生殖功能受损的机制进行综述。     

虎门镇异位妊娠患者生殖健康状况及其相关知识调查

目的了解异位妊娠患者的生殖健康状况和健康知识需求。方法对虎门镇2家“二甲”医院就诊的496例异位妊娠患者进行生殖健康状况检查和生殖健康知识及需求的问卷调查。结果77.3%的患者合并生殖系统感染,19.0%的患者有过2次以上的人工流产史;影响生殖健康的危险因素依次为:急、慢性宫颈炎,急、慢性盆腔炎/附件炎,多次人流,剖宫产史。生殖系统感染、人工流产与异位妊娠关系及生殖系统感染的预防等方面知识的知晓率低,从不检查治疗者高达58.13%。生殖健康知识需求主要为生殖系统感染的危害、人流危害和避孕知识。期望获取的途径主要为医院咨询门诊和报纸杂志。结论异位妊娠患者存在生殖健康问题,需要进行生殖健康知识教育和提供生殖健康服务。     

Environmental mercury exposure,semen quality and reproductive hormones in Greenlandic Inuit and European men: a cross-sectional study

Several animal studies indicate that mercury is a male reproductive toxicant, but human studies are few and contradictory. We examined semen characteristics and serum levels of reproductive hormones in relation to environmental exposure to mercury. Blood and semen samples were collected from 529 male partners of pregnant women living in Greenland, Poland and Ukraine between May 2002 and February 2004. The median concentration of the total content of mercury in whole blood was 9.2 ng ml⁻¹ in Greenland (0.2–385.8 ng ml⁻¹), 1.0 ng ml⁻¹ in Poland (0.2–6.4 ng ml⁻¹) and 1.0 ng ml⁻¹ in Ukraine (0.2–4.9 ng ml⁻¹). We found a significantly positive association between the blood levels of mercury and serum concentration of inhibin B in men from Greenland (β=0.074, 95% confidence interval (CI)=0.021 to 0.126) and in an analysis including men from all three regions (β=0.067, 95% CI=0.024 to 0.110). The association may be due to beneficial effects of polyunsaturated fatty acids (PUFAs), which are contained in seafood and fish. No significant association (P>0.05) was found between blood concentrations of mercury and any of the other measured semen characteristics (semen volume, total sperm count, sperm concentration, morphology and motility) and reproductive hormones (free androgen index (FAI), follicle-stimulating hormone (FSH), luteinizing hormone (LH), testosterone and LH×testosterone) in any region. In conclusion, the findings do not provide evidence that environmental mercury exposure in Greenlandic and European men with median whole blood concentration up to 10 ng ml⁻¹ has adverse effects on biomarkers of male reproductive health.     

慢性阻塞性肺病急性加重期动态血压监测的临床意义

目的　观察慢性阻塞性肺病 (COPD)急性加重期病人 2 4h动态血压变化规律 ,探讨影响其血压变化的因素。方法　 6 2例COPD急性加重期病人根据动脉血气分析结果分成低PO2 正常PCO2 组 (A组 )、低PO2 高PCO2 组 (B组 )、低PO2 低PCO2 组 (C组 )和正常PO2 高PCO2 组 (D组 )。各组病人均进行 2 4h动态血压监测和血糖、皮质醇、T3 等测定 ,将检测结果在各组间进行统计学分析 ,观察不同组病人动态血压及其昼夜变化规律与动脉血气分析和血皮质醇及T3 水平变化的关系。结果　B组和D组病人收缩压、舒张压和皮质醇浓度明显升高 (与其他各组比较P <0 0 5 ) ,T3 明显降低 ,而且皮质醇浓度与收缩压和PCO2 呈明显正相关。此外 ,动态血压昼夜变化规律为 :B组非勺型血压曲线发生率最高 ,以下依次为D组、C组和A组。结论　PCO2 增高可能是COPD急性加重期病人血压升高和非勺型血压曲线增加的主要原因。     

高血压患者血压昼夜节律分析

目的探讨高血压患者血压昼夜节律的变化。方法采用24 h动态血压监测(ABPM)技术研究高血压患者昼夜节律变化特点并与正常人比较。结果单纯高血压组(EH)与正常组比较,血压昼夜节律改变两组无明显差异。而原发性高血压伴靶器官损害组(TOD)的昼夜节律与单纯高血压组或正常组比较差异有显著意义(P<0.01)。结论血压昼夜节律变化与TOD密切相关。     

Fluvastatin combined with benazepril may contribute to the favorable prognosis of patients with atrial fibrillation

The aim of this study was to observe the clinical efficacy of fluvastatin combined with benazepril in the treatment of patients with atrial fibrillation (AF). A total of 92 patients with AF were randomly assigned to the case group (n = 46), in which the patients were treated with fluvastatin (80 mg) plus benazepril (10 mg), or to the control group (n = 46), in which the patients were treated with fluvastatin (80 mg). The conversion rate of sinus rhythm was higher in the case group than in the control group (P < 0.05). The case group had more treatment-effective patients than the control group, with fewer treatment-ineffective patients (P < 0.05). The LVEDd, LVESd, LAD, and LVEF indexes in the case group were lower than in the control group after 6 months of treatment (all P < 0.05). Levels of hs-CRP were also lower in patients in the case group than in patients in the control group after 1 month of treatment (P < 0.05). After 12 months, renin and Ang II concentrations were lower in patients in the case group than in the control group (both P < 0.05). Significant differences in IL-6 and TNF-α expression were found between the two groups after 1 month, 6 months, and 12 months of treatment (all P < 0.05). Compared to patients in the control group, the levels of total cholesterol (TC), triglycerides, and LDL-C in the case group were lower after 6 and 12 months of treatment (all P < 0.05), while the HDL level was higher (P < 0.05). Treatment with fluvastatin combined with benazepril further increased the conversion rate of sinus rhythm and significantly improved the quality of life and prognosis of AF patients.     

Mycardial ischemia and determined chaos in integral homeostatic regulation

This study was devoted to the problem of homeostatic stability loss caused by myocardial ischemia, induced by stress testing. It involved 55 patients with different variants of coronary heart disease and 15 practically healthy volunteers as controls. Routine bicycle ergometry and nonstop monitoring of the cardiac-interval duration were conducted simultaneously. The systemic homeokinetic state was evaluated by means of cardiac rhythm entropy dynamics analysis in a multidimensional space of existence. Determined chaos was shown to be the main property of these dynamics in all cases. The original method of measuring the cardiac rhythm entropy chaotisity level is presented. It is suggested that the newly revealed phenomenon of a sharp rise in the cardiac entropy trajectory chaotisity level and followed by a decrease, which happens in the multidimensional phase space, may be used as an additional criterion of myocardial ischemia development for the verification of dubious stress-testing results.